blood platelets

Platelets to be discussed include the structure of the platelet, platelet count, platelet function, and restrictions on platelet function.

Structure of PlateletsPlatelets are a part and a few large cells in bone marrow are disc-shaped round, oval, bikonveks, not cored, and live about 10 days.

Number of PlateletsPlatelet counts between 150 and 400 x 10 "9/liter (150.000-400.000/mitiliter), approximately 30-10% dalain concentrated in the spleen and the rest circulates in the blood.

Platelet FunctionPlatelets play an important role in the formation of blood clots. Platelets normally circulate throughout the body through the bloodstream. However, within a few seconds after a blood vessel damage, platelets are attracted to the area in response to the collagen layer displayed in subendotel vessels. Platelets adhere to the surface is damaged and removed some substances (serotonin and histamine) that cause vascular vasoconstriction.

Another function of platelets is to change the shape and quality after which binds to vascular injury. Platelets to become sticky and clump together to form a platelet plug which effectively patching the wound area.

Platelet Function LimitationExcessive accumulation of platelets can cause decreased blood flow to the network or plug becomes very large, so out of place was, and the flow to the downstream as an embolus and block the flow downstream.

In order to prevent the formation of an embolism, it is generating platelet-platelet materials that limit their own extensive clumping. The main ingredient is released by platelets for clotting limit is prostaglandin thromboxane A2 and prostacyclin 12. Thromboxane A2 stimulate the breakdown of platelets and cause further vasoconstriction in blood vessels. While prostacyclin 12 stimulates platelet aggregation and vessel dilation, thereby further improving the response of platelets.

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